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Molecular Residual Disease (MRD): Exploring the impact on cancer early detection and personalized care

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In this session, delve into the cutting-edge science of Molecular Residual Disease (MRD) testing, a revolutionary approach to cancer detection and treatment guidance. Leaders in the field will discuss the history of MRD – its foundations in clinical medicine – and where the opportunities exist for further research and application. We’ll explore how these tests can help determine prognosis/relapse risk, find early recurrence and individualize treatment to improve patient outcomes.

Learning Objectives:

1.  Explain what molecular residual disease (MRD) is and implications for earlier detection and secondary prevention
2.  Cite two examples of how MRD is utilized for recurrence
3.  Understand what CTDNA is and how it is used to find MRD
4.  Identify how MRD is currently being used, and what potential applications are currently being researched 

Heather Parsons, M.D., MPH

Clinical Research Division, Fred Hutch Cancer Center and the Department of Medicine, University of Washington

Heather A. Parsons, MPH, MD, is Program Director in Breast Oncology, the Maudslien Endowed Chair in Breast Cancer Precision Oncology Research, and Associate Professor in the Clinical Research Division at Fred Hutch Cancer Center and the Department of Medicine at the University of Washington. She is an Associate Member in the Cancer Program at the Broad Institute of MIT and Harvard. A nationally recognized expert in breast cancer and precision oncology, Dr. Parsons leads pioneering research in circulating tumor DNA (ctDNA) and liquid biopsy technologies, with a particular focus on minimal residual disease (MRD) detection and its clinical applications. Her work has shaped multiple clinical trials and translational studies aimed at improving outcomes for patients with HER2-positive and metastatic breast cancer. She serves in leadership roles across national research consortia and guideline committees, and her contributions have been widely published in high-impact journals.

Amir Jazaeri, M.D.

Department of Gynecologic Oncology and Reproductive Medicine, University of Texas MD Anderson Cancer Center

Dr. Jazaeri is a Professor and the Vice Chair for Clinical Research in the Department of Gynecologic Oncology and Reproductive Medicine at the University of Texas MD Anderson Cancer Center.  He also serves as the Director of the Gynecologic Cancer Immunotherapy Program. In addition to novel immunotherapies for gynecologic cancers, his other areas of research interest include investigation of the minimal residual disease phase of ovarian cancer, and innovative clinical trial designs.

Jeff Gregg, M.D.

Foresight Diagnostics

Dr. Jeffrey Gregg is Vice President of Medical Affairs at Foresight Diagnostics, where he focuses on medical affairs strategy, evidence generation, and medical education for ctDNA-based measurable residual disease (MRD) testing. He previously served as Professor of Pathology at UC Davis School of Medicine, where he also directed clinical pathology and molecular diagnostics programs. With more than 25 years of experience in oncology diagnostics, Dr. Gregg has held senior leadership roles at Biofidelity, Harbinger Health, Freenome, and Foundation Medicine. He has authored over 100 peer-reviewed publications in molecular diagnostics and precision oncology and is a frequent speaker at national and international oncology meetings.

Lauren Leiman

BLOODPAC

Lauren C. Leiman, MBA is currently the Executive Director of the Blood Profiling Atlas in Cancer (BLOODPAC), a consortium focused on creating an open database for liquid biopsies to accelerate the development of safe and effective blood profiling diagnostic technologies for patient benefit.  Lauren received her undergraduate degree in communications from the University of Pennsylvania's Annenberg School. She also holds an MBA in international business from the University of North Carolina's Kenan-Flagler Business School and a master's degree in public relations and corporate communications from NYU. Through her work with BLOODPAC, Lauren has numerous publications many of which are in the liquid biopsy space. 

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Webinar
10/08/2025 at 1:00 PM (EDT)  |  90 minutes
10/08/2025 at 1:00 PM (EDT)  |  90 minutes In this session, speakers will delve into the cutting-edge science of Minimal Residual Disease (MRD) testing, a revolutionary approach to cancer detection. We’ll explore how these tests can help determine prognosis/relapse risk, find early recurrence and individualize treatment to improve patient outcomes.
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Program Evaluation for Minimal Residual Disease (MRD): Exploring the impact on cancer early detection and personalized care
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Sponsored by the Prevent Cancer Foundation (provider number 125052), a designated provider of Continuing Education Contact Hours (CECH) in health education by the National Commission for Health Education Credentialing, Inc., this program is designated for Certified Health Education Specialists (CHES®) and/or Master Certified Health Education Specialists (MCHES®) to receive up to 1.5 total Category I CECH. Content will be provided in the following areas of responsibility for health education specialists: Area V: Advocacy. 

This activity has been evaluated and approved by the Continuing Education Approval Program of the National Association of Nurse Practitioners in Women's Health for 1.5 CE continuing education contact hours. NPWH Activity number 25-09-03. CA CEP Number 13411.